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The EpiSonic? 2000 Sonication System is the latest sonication-based instrument with integrated cooling for DNA shearing and chromatin shearing applications. This sonicator is designed for simultaneous, optimized processing of 1 to 12 samples at small microliter-level volumes (optimal at 15 μl of volume), making it an ideal solution for next-generation sequencing due to its high shearing consistency and uniformity.
Features At-A-Glance
The EpiSonic? 2000 incorporates Digitally Adaptive Sonocavitation? (DAS) technology to efficiently process DNA and chromatin samples, with the following key features:
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Simple input and controls
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Simultaneous sonication of up to 12 samples
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10 minutes to shear 12 samples to 300 bp (50 sec/sample)
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Reproducible and consistent fragments
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Closed vessel processing
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Easy installation and maintenance
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Continuous cooling system
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20-month warranty
Key Points
Notable points of the EpiSonic? 2000 include the following:
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Generates fragments compatible with Illumina, Ion Torrent, 454, and Pacific Biosciences platforms.
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Generates tight and highly reproducible fragment distributions.
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Capable of achieving uniform fragment sizes between 150 bps and 20 kbs.
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Meets "the scientist's requirements" for a low-cost, flexible, higher throughput and easy-to-use design.
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Eliminates operator-induced variations, improves recovery yield, increases efficiency, and provides results that can be standardized.
 Fig. 2. Demonstration of consistent fragments achieved with a single run of 12-sample multiplex shearing with the EpiSonic? 2000.
DAS? technology, incorporated into the EpiSonic? 2000, provides the following advantages:
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Controlled energy delivery
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Isothermal environment
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Non-contact, closed vessel processing
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Enhanced reproducibility
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Uniform multiplex sample shearing
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User selectable fragment lengths
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High sample recovery with no heat damage
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No cross-contamination, no aerosols, no clean up
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Micro-scale sample volumes
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Real-time process monitoring
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Fig. 1. Setup of the EpiSonic? 2000 Sonication System.
Specifications
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Model Number
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2000
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Input Voltage
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100-120 VAC or 220-240 VAC @ 50/60 Hz
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Power Rating
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750 Watts
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Programmable Timer
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Up to 10 hours
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Operating Frequency
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20 kHz
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Timer Control
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Digital
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Throughput Capability
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Up to 12
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Chiller Dimensions
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7.5"L x 5"W x 7"H (19 cm x 12.7 cm x 17.6 cm)
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Generator Dimensions
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15.25"L x 8"W x 8.5"H (38.7 cm x 20.3 cm x 21.6 cm)
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Sound Enclosure Dimensions
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10"L x 10"W x 16.5"H (25.5 cm x 25.5 cm x 42 cm)
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Operating Environment
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Temperature: 39°-95°F (4°-35°C)
Relative Humidity 20-90% (Non Condensing)
For indoor use only
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Origin of Manufacture
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USA
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Warranty Period
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20 months
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